Office: B222
Lab: B280
Lab Phone: 303-492-2369
Lab Fax: 303-492-5894
PhD: Caltech 1993
Postdoctoral Fellowship:聽The Scripps Research聽Institute 1993 - 1996
Honors and Awards:聽NSF Predoctoral Fellowship, NSF Postdoctoral Fellowship, NSF Career Award, University of baby直播app Junior Faculty Development Award, Beckman Young Investigator, Research Corporation Young Investigator Award
Research Interests:聽Structural biology, NMR, telomere biology and biochemistry, viral replication, action of the estrogen receptor, small molecule screening
Teaching Interests:聽Honors General Chemistry, Physical Chemistry with Biological Applications, Graduate Core Biochemistry, Graduate Biophysics
Our research program at the University of baby直播app is poised at the interface of biochemistry, biophysics and biology. Our lab aims to understand the underlying molecular mechanisms behind important biological processes. Recently, we have focused our efforts on telomere biology, attempting to understand the structural and biochemical basis for the maintenance of the ends of chromosomes. Disruption of telomere maintenance is catastrophic for the cell, and telomere processes are linked to both cancer and aging. We are also studying viral replication in the picornavirus family and the ligand binding properties of the estrogen receptor. A common theme is bringing sophisticated structural and biochemical tools to complex biological systems.